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Hey everybody, welcome to my homepage. I am currently a postdoc at the lab of
Dr. Ursula Jakob
in the MCDB department of the University of Michigan, Ann Arbor, MI,
US.
I am currently working on projects dealing with redox regulation and chaperones.
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I did B.Sc. in Faculty of Biology in the Tel Aviv University and M.Sc. in The Weizmann Institute of Science in Dr. Shmuel Pietrokovski laboratory.
In my Master research I tried to connect between computers and biology by
doing sequence analysis and characterization of conserved protein regions. During my PhD studies I studied biophysical rules governing
protein-protein at the lab of
Prof. Gideon Schreiber
in the Biological Chemistry department of The Weizmann Institute of Science,
Rehovot Israel.
In addition, I worked on issues that relate to protein-surface interactions in collabiration with lab
of Prof. Israel Rubinstein
publications:
CV
AQUAPROT server - definition of the interface residues and related water molecules
NUMODs Motif Finder (by Einat Sitbon)
Email:
The modular architecture of protein-protein binding interfaces.
Proc Natl Acad Sci U S A. 2005,102(1):57-62
abstract
Binding hot spots in the TEM1-BLIP interface in light of its modular
architecture,
J. Mol. Biol. 2007, 365(3):663-79 abstract
The molecular architecture of protein-protein binding sites.
Curr Opin Struct Biol. 2007, 17:1-10 . abstract
On the contribution of water-mediated interactions to protein-complex
stability.
Biochemistry Journal. 2008, 47(3):1051-60. abstract
Similar chemistry but different bond preferences in inter versus
intra-protein interactions.
*Equal contribution, Proteins, 2008;72(2):741-53. abstract
Computational redesign of a protein-protein interface using its modular
architecture, J. Mol. Biol., 2008,384(1):109-19
*Equal contribution. abstract
A global benchmark study using affinity-based biosensors, Analytical Biochemistry 2008, 386(2):194-216 abstract
Unfolding of metastable linker region is at the core of Hsp33's activation as a redox-regulated chaperone, J Biol Chem 2010. abstract
Evaluating the binding of peptides to gold surfaces in real time, submitted
Substrate Binding Specificity of The Redox-Regulated Chaperone Hsp33, in preparation.
Servers
Destruction box motif site
Other Links
PROSURF project
My
bookmarks
my details are:
phone +1 (734) 615 1957
+1 (734) 757 0511
FAX +1 (734) 615 4226
ADDRESS University of Michigan
MCDB
Natural Science Building, Room 4041
830 N. University
Ann Arbor, MI 48109
USA