| Protein host | Intein integration point |
Species * | Mj | Ph | Pf | Pa | Mk | Mb | Ma | Mt | Af | Hs | Hm | Hv | Ta | Tv | Fa | Fs | Pt | Ap | Ss | Pa | Ne |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Translation initiation factor bIF-2 | IF2-a | Y | Y | Y | Y | Y | ||||||||||||||||
| KlbA virulence protein | klbA-a | Y | Y | Y | Y | |||||||||||||||||
| DNA reverse gyrase/DNA topoisomerase I 1 | r-gyr-a | Y | Y | Y | ||||||||||||||||||
| topA-a | Y | |||||||||||||||||||||
| Unknown function, gene rtcB (MJ0682, PH1602, PAB0383) | rtcB-a | Y | Y | Y | Y | Y | ||||||||||||||||
| Replication factor C, 37 Kd subunit | RFC-a | Y | Y | Y | Y | |||||||||||||||||
| RFC-b | Y | Y | ||||||||||||||||||||
| RFC-c | Y | Y | ||||||||||||||||||||
| DNA polymerase family B (archaeal polA gene) | pol-a | Y | ||||||||||||||||||||
| pol-b | Y | Y | Y | Y | ||||||||||||||||||
| pol-c | Y2 | |||||||||||||||||||||
| Vacuolar-type ATPase catalytic subunit | VMA-b | Y | Y | Y | Y | Y | Y | Y | ||||||||||||||
| Vacuolar-type ATPase beta subunit | VatB-a | Y | ||||||||||||||||||||
| DNA repair protein radA (RAD51, recA homolog) | recA-c | Y | ||||||||||||||||||||
| ATP-dependent protease LA (lon gene) | lon-a | Y | Y | Y | ||||||||||||||||||
| Archaeal DNA polymerase Pol II, DP2 subunit (Archaeal polC gene) | polC-a | Y | Y | Y | Y | |||||||||||||||||
| Cell division control protein 21 (CDC21) | CDC21-a | Y | Y | Y | Y | |||||||||||||||||
| CDC21-b | Y | Y | Y | |||||||||||||||||||
| Cell division control protein 48 (CDC48 ATPase) | CDC48-a | Y | ||||||||||||||||||||
| class-II Ribonucleotide reductase | RIR1-a | Y | Y | |||||||||||||||||||
| RIR1-b | Y | Y | Y | Y | Y | Y | ||||||||||||||||
| RIR1-c | Y | |||||||||||||||||||||
| Molybdenum cofactor biosynthesis protein A | moaA-a | Y | ||||||||||||||||||||
| Similar to phage terminase large subunits | terA2-a | Y | ||||||||||||||||||||
| Unknown function InterPro UPF0051 family (pps1 proteins) | pps1-b | Y | Y | |||||||||||||||||||
| Unknown function - APE0745 | hyp3-a | Y | ||||||||||||||||||||
| LHR - large helicase-related protein | LHR-a | Y | ||||||||||||||||||||
| An ATP dependent helicase (MJ1124) | helicase-a | Y | ||||||||||||||||||||
| Phosphoenol pyruvate synthase | PEPsyn-a | Y | ||||||||||||||||||||
| Transcription factor IIB | TFIIB-a | Y | ||||||||||||||||||||
| UDP-glucose dehydrogenase | UDPGD-a | Y | ||||||||||||||||||||
| Unknown function | hyp1-a | Y | ||||||||||||||||||||
| Glutamine fructose 6 phosphate transaminase | GF6P-a | Y | ||||||||||||||||||||
| class-III (anaerobic) Ribonucleotide reductase | RNR-a | Y | ||||||||||||||||||||
| RNR-b | Y | |||||||||||||||||||||
| RNA polymerase subunit A' | RpolA'-a | Y | ||||||||||||||||||||
| RNA polymerase subunit A" | RpolA"-a | Y | ||||||||||||||||||||
| Totals: 28 | 37 | 19 | 14 | 10 | 14 | 5 | 1 | 0 | 1 | 0 | 2 | 4 | 1 | 1 | 1 | 2 | 3 | 1 | 1 | 0 | 0 | 1 |
| Y | : intein is present in this insertion point and species. |
| : this insertion point in this species does not have an intein. | |
| : intein host has no corresponding gene (ortholog) in this species. |
1The r-gyr-a intein integration
point is found in the same position at homologous domains in DNA reverse
gyrase (in Mja and Pho) and in DNA topoisomerase I (in Pfu).
2 The Nanoarchaeum equitans polA DNA polymerase is
split into two genes and includes a split-intein that is assumed to join
the two protein parts.
* Species descriptions:
| Mj | - Methanocaldococcus jannaschii DSM 2661 | Euryarchaeota; Methanococcales | Anaerobic, H2-dependent autotrophic methanogen, hyperthermophilic (85° C) |
| Ph | - Pyrococcus horikoshii OT3 | Euryarchaeota; Thermococcales | Anaerobic, hyperthermophilic (98° C) |
| Pf | - Pyrococcus furiosus | Euryarchaeota; Thermococcales | Anaerobic, hyperthermophilic (100° C) |
| Pa | - Pyrococcus abyssi GE5 | Euryarchaeota; Thermococcales | Anaerobic, hyperthermophilic (103° C) |
| Mk | - Methanopyrus kandleri AV19 | Euryarchaeota; Methanopyrales | Anaerobic, H2-dependent autotrophic methanogen, hyperthermophilic (80-110° C) |
| Mb | - Methanococcoides burtonii DSM6242 | Euryarchaeota; Methanosarcinales | Anaerobic, methanogen, psychrotolerant (<4-29° C) |
| Ma | - Methanosarcina acetivorans C2A | Euryarchaeota; Methanosarcinales | Anaerobic, acetate-utilizing methanogen, mesophilic (35° C) |
| Mt | - Methanothermobacter thermautotrophicus DH | Euryarchaeota; Methanobacteriales | Anaerobic, H2-dependent autotrophic methanogen, thermophilic (65° C) |
| Af | - Archaeoglobus fulgidus DSM 4304 | Euryarchaeota; Archaeoglobales | Anaerobic, sulphate-reducing, hyperthermophilic (83° C) |
| Hs | - Halobacterium sp. NRC-1 | Euryarchaeota; Halobacteriales | Aerobic, extreme halophile (3-5 M NaCl), chemoorganotroph, phototrophic, mesophilic (37° C) |
| Hm | - Haloarcula marismortui ATCC43049 | Euryarchaeota; Halobacteriales | Aerobic, extreme halophile, mesophilic |
| Hv | - Haloferax volcanii DS2 ATCC29605 | Euryarchaeota; Halobacteriales | Aerobic, extreme halophile, mesophilic |
| Ta | - Thermoplasma acidophilum DSM 1728 | Euryarchaeota; Thermoplasmales | Microaerophilic, acidophilic (pH 2), heterotrophic, hyperthermophilic (59° C) |
| Tv | - Thermoplasma volcanium GSS1 | Euryarchaeota; Thermoplasmales | Aerobic and unaerobic, acidophilic (pH 2), heterotrophic, hyperthermophilic (60° C) |
| Fa | - Ferroplasma acidiphilum fer1 | Euryarchaeota; Thermoplasmales | Anaerobic hyperacidophilic (pH 1.0), chemoorganotrophic and chemomixotrophic - ferrous-iron-oxidizing, mesophilic (42° C) |
| Fs | - Ferroplasma species type II | Euryarchaeota; Thermoplasmales | Anaerobic hyperacidophilic (pH 1.0), chemoorganotrophic and chemomixotrophic - ferrous-iron-oxidizing, mesophilic (42° C) |
| Pt | - Picrophilus torridus DSM 9790 | Euryarchaeota; Thermoplasmales | Aerobic, thermophilic (60°C), hyper-acidophilic (pH 0.7) |
| Ap | - Aeropyrum pernix K1 | Crenarchaeota; Desulfurococcales | Aerobic, hyperthermophilic (95° C) |
| Ss | - Sulfolobus solfataricus P2 | Crenarchaeota; Sulfolobales | Aerobic, acidophilic (pH 5), hyperthermophilic (85° C) |
| Pa | - Pyrobaculum aeropyrum IM2 | Crenarchaeota; Thermoproteales | Aerobic, nitrate-reducing, hyperthermophilic (100° C) |
| Ne | - Nanoarchaeum equitans Kin4-M | Nanoarchaeota; | Anaerobic, obligate symbiont (of the crenarchaeon Ignicoccus spp.) hyperthermophilic (90° C) |